The Integrative Cardiac Biomechanics Laboratory is led by Dr. Stuart Campbell and located within the department of Biomedical Engineering at Yale University. We conduct translational research at the intersection of several disciplines, including cardiac muscle physiology, biomechanics, biophysics, tissue engineering, stem cell biology, and clinical cardiology. We have a passion for creating novel computational models, laboratory devices, and experimental methods to solve unmet clinical needs and address challenging questions in the realm of basic cardiac physiology.  Current areas of research interest include:
Inherited Cardiomyopathies – Discovering detailed disease mechanisms, predicting genotype-phenotype relationships, and improving clinical diagnostics/therapeutics.
Cardiomyocyte Function and Heterogeneity – Characterizing cell-to-cell variation in the myocardium and studying the cellular signaling pathways that regulate muscle contraction.
Cardiac tissue mechanobiology – Dissecting the role of biomechanical loads and extracellular matrix on cardiac remodeling and mechanotransduction.
You can learn more about each of these research areas, find recent lab publications, and meet current lab members in the following pages.


July 24, 2019
When it comes to heart disease, the health of the scaffold where cardiac cells grow may be a much bigger factor than previously believed. Stuart Campbell, associate professor...
January 31, 2019
There are many ways to frame the forces that shape this Sunday’s Super Bowl - East Coast vs. West Coast, dynasty (the New England Patriots) vs. upstarts (the Los Angeles Rams...
January 19, 2018
What kind of biomaterials would promote the growth of cardiac tissue? How do you make cells properly mature outside the body in a matter of weeks? Discussions on these and...